Quality of life against seasonal vs perennial allergens: ESPRINT-15 modified in the pediatric population

Introduction: Allergic rhinitis (AR) is a clinical syndrome characterized by IgE-mediated inflam-mation of the nasal mucosa. The present study investigates the quality of life (QoL) with AR among adults, using widely validated questionnaires, unlike in pediatric patients.Materials and methods: A cross-sectional descriptive observational study was conducted, analyzing the QoL of 102 children with AR aged between 10-15 years, belonging to two health centers (HC) in Zaragoza and two HC in Coruña. The comparison of means between the two groups is carried out using the Student's test or the Mann-Whitney test, considering a value of p<0.05 to be significant.Results: Around 102 children were studied, with a majority (59.8%) being male and a mean age of 12 years. Around 76.5% have a family history of atopy. It was found that AR is more prevalent in Zaragoza (p <0.005), and asthmais highly prevalent in Coruña (p <0.001). The most import-ant sensitizations are pollen in Zaragoza (p <0.05) and dust mites in A Coruña (p <0.001). More treatment needs and associated comorbidities (p<0.05) were observed in A Coruña. The results of the ESPRINT-15 show that 63% of the patients have a good QoL, 27% fair, and 8.8%, poor. Those sensitized to mites have a worse score (p = 0.02). It was found that 52% of children expe-rienced improvement during home confinement, with no notable differences between the two populations. The use of the mask favored QoL in patients from Zaragoza (p <0.0 01 (AU)

[Cases of heart failure requiring hospitalization]. / Estudio de los casos de insuficiencia cardíaca que han requerido ingreso hospitalario.

OBJECTIVE: To find the characteristics of patients with heart failure requiring admittance to the referral hospital for the A Coruña Health Area. DESIGN: Descriptive, crossover and retrospective study. SETTING: Health area of 500,000 inhabitants. PATIENTS AND OTHER PARTICIPANTS: Patients admitted with diagnosis of heart failure (1995; n = 636). A simple randomised sampling was undertaken, stratified by sex (n = 225; alpha = 0.05; accuracy = 6%). Sample size was increased by 25% due to possible losses of information. MEASUREMENTS AND MAIN RESULTS: The most common underlying causes were: ischaemic cardiopathy 36.4%, dilated myocardiopathy 23.6% and hypertension 16.5%. The most common catalysing factors were: infection 32.6% and tachycardia 24.6%. The commonest symptoms were dyspnoea 90.6% and orthopnoea 63.9%. The most frequent sign was crepitus 79.8%, followed by oedemas 58.3%. An echocardiogram was performed on 42.6% and 22% had digoxinaemia. Most common linked pathology was: hypertension 33.5% and COPD 25.0%. After admission the use of diuretics (30%), digoxin (9%) and ACE inhibitors (27%) was increased. 7.7% of patients died. Variables most commonly linked to death were myocardial infarction (OR = 21.8), hyponatraemia (OR = 12.2) and kidney failure (OR = 7.04). CONCLUSIONS: Given the underlying causes and catalysing factors seen in the results of this study, family doctors play a decisive role in prevention and control of heart failure.